國立臺灣大學生態學與演化生物學研究所

Institute of Ecology and Evolutionary Biology
National Taiwan University

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Cheng-Ruei Lee, Assistant Professor (李承叡 助理教授)


Title: Assistant Professor

Education: Ph.D. Duke University, USA

Interest: Evolutionary genetics, Evolutionary genomics, Quantitative genetics, Genetic mapping

E-mail: chengrueilee@ntu.edu.tw

Lab: Life Science Building R1129

Tel: +886-2-33662535

Lab Web: https://sites.google.com/site/chengrueilee/


Research Interests

  1. The genetic and genomic changes underlying weedy plant evolution.
  2. The evolution of wild relatives of important economical species.

Lab Introduction

Our lab is interested in any topic broadly related with evolutionary and ecological genetics and genomics, specifically, how do genes, genomes, environments, complex traits, and natural selection interact with and shape the patterns of each other? What is your favorite species? Let's explore the interesting story behind it!

We use a highly integrative and interdisciplinary approach for our research, incorporating knowledge and techniques in field ecology, population genetics, quantitative genetics, molecular biology, genomics, and bioinformatics. Perspective students are expected to be enthusiastic about evolution. Having prior knowledge of any of these fields is great, but not necessary.

We are interested in (but not limited to) these important questions:

Does local adaptation facilitate speciation?

Why is there genetic variation, and what maintains it?

What are the factors shaping geographical patterns of genomic variation?

Some genomic regions are more polymorphic than others. Why?

What are the genomic regions or genes controlling adaptive traits?

Are they few genes each with large effect, or many genes each with small effect?

Does the adaptive allele come from novel mutation or standing genetic variation?

In addition, we are also interested in the evolution and relationship of human-associated plants with their wild relatives, including the weed Arabidopsis thaliana and economically important species such as rice and soybean. Our group highly welcome those who are interested in ecological and evolutionary genetics and genomics!


Courses offered

EEB5035 Evolution
EEB5045 Population Genetics
EEB5087 Molecular Evolution

Publications (See the full list of publications in my website)

Hsu, C-W, C-Y Lo, C-R Lee. 2019. On the post-glacial spread of human commensal Arabidopsis thaliana: journey to the east. New Phytologist 222(3):1447-1457

Lee, C-R, J-W Hsieh, ME Schranz, T Mitchell-Olds. 2018. The functional change and deletion of FLC homologs contribute to the evolution of rapid flowering in Boechera stricta. Frontiers in Plant Science 9:1078

Lee, C-R, B Wang, J Mojica, T Mandáková, KVSK Prasad, JL Goicoechea, N Perera, U Hellsten, HN Hundley, J Johnson, J Grimwood, K Barry, S Fairclough, JW Jenkins, Y Yu, D Kudrna, J Zhang, J Talag, W Golser, K Ghattas, ME Schranz, R Wing, MA Lysak, J Schmutz, DS Rokhsar, T Mitchell-Olds. 2017. Young inversion with multiple linked QTLs under selection in a hybrid zone. Nature Ecology & Evolution 1:0119

Lee, C-R, H Svardal, A Farlow, M Exposito-Alonso, W Ding, P Novikova, C Alonso-Blanco, D Weigel, M Nordborg. 2017. On the post-glacial spread of human commensal Arabidopsis thaliana. Nature Communications 8:14458

The 1001 Genomes Consortium. 2016. 1135 genomes reveal the global pattern of polymorphism in Arabidopsis thaliana. Cell 166:481-491

Lee, C-R, JT Anderson, and T Mitchell-Olds. 2014. Unifying genetic canalization, genetic constraint, and genotype-by-environment interaction: QTL by genomic background by environment interaction of flowering time in Boechera stricta. PLoS Genetics 10(10):e1004727

Lee, C-R and T Mitchell-Olds. 2013. Complex trait divergence contributes to environmental niche differentiation in ecological speciation of Boechera stricta. Molecular Ecology 22(8):2204-2217

Lee, C-R and T Mitchell-Olds. 2012. Environmental adaptation contributes to gene polymorphism across the Arabidopsis thaliana genome. Molecular Biology and Evolution 29(12):3721-3728

Prasad, K, B-H Song, C Olson-Manning, JT Anderson, C-R Lee, ME Schranz, AJ Windsor, MJ Clauss, AJ Manzaneda, I Naqvi, M Reichelt, J Gershenzon, SG Rupasinghe, MA Schuler, and T Mitchell-Olds. 2012. A gain-of-function polymorphism controlling complex traits and fitness in nature. Science 337:1081-1084

Lee, C-R and T Mitchell-Olds. 2011. Quantifying effects of environmental and geographical factors on patterns of genetic differentiation. Molecular Ecology 20(22):4631-4642

en/crlee/start.txt · Last modified: 2017/02/24 23:24 (external edit)